Definition
Circadian rhythm
The roughly 24-hour internal clock, entrained primarily by light exposure, that governs sleep timing, hormone release, and metabolism.
From the episode “Chronic Insomnia: Almost None Get Treated — Colin Lawlor on the Sleep Data Gap”Hear it on the podcast1 episode
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China clay (kaolin)The white clay mined in Cornwall for 275 years; the Trelavour lithium project sits in a former china clay pit.Chronic insomniaPersistent difficulty falling or staying asleep. Colin cites 800 million people worldwide, mostly untreated, though global prevalence estimates vary widely by definition.ChronotherapyTiming a medical treatment to the patient's circadian rhythm. Evidence is genuinely mixed.ChronotypeYour biological bias toward mornings or evenings, morning bird, night owl, or somewhere between. Colin's argument is that prescribing 6am workouts to a night owl is prescribing failure.CLIAClinical Laboratory Improvement Amendments, a federal certification program covering labs. A CLIA registered lab can develop and run a test in-house and sell the result, separate from FDA device approval.Clinical Documentation AutomationAI-powered transcription and note generation that listens to provider-patient conversations and produces structured clinical notes, reducing administrative burden and freeing clinicians to focus on the patient rather than the keyboard.Clinical InferenceAn AI-generated probabilistic assessment of a patient's health status or risk level, derived from multiple data inputs. Not a diagnosis — a statistically grounded estimate ('the likelihood of this person having hypertension is above population average') that requires clinician review before any action is taken. Axenya generates 95 million clinical inferences per month across its monitored population. The key distinction: a clinical inference routes a patient toward care; a diagnosis determines what care they receive. The former is automatable at scale; the latter requires physician judgment.CoFIDComposition of Foods Integrated Dataset, the UK government's official food nutrition database, used alongside USDA data in Qalzy's 2.9 million item database.